The Mandate

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New Vax may be getting approved. Non-mRNA design.


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(CNN)The world could soon have another vaccine option in its fight against Covid-19.
European drug makers Sanofi and GSK announced positive results from late-stage clinical testing of a new vaccine that will be named Vidprevtyn, according to a Sanofi spokesperson. The companies plan to seek authorization for the shots in the US and Europe.

Vidprevtyn is a protein subunit vaccine, which means it uses harmless protein fragments that teach the immune system how to spot and fight off the SARS-CoV-2 virus. It's a more traditional type of vaccine than mRNA or adenovirus vector vaccines, which carry the genetic instructions for making the spike protein into cells, where they can then be built and displayed like mug shots for the immune system find and defend against.
These kinds of vaccines can be stored at refrigerator temperatures, making them easier to use in areas that don't have access to ultracold storage. Because they rely on more familiar technology, there's hope that people who've declined other kinds of Covid-19 vaccines may find these kinds of vaccines more palatable.

Promising study results​

The vaccine is given in two doses delivered about three weeks apart. The phase 3 trials to test the vaccine enrolled more than 10,000 adults in the US, Asia, Africa and Latin America. A separate study is assessing a third dose of the vaccine as a booster.

After two doses given to people with no antibodies against the SARS-CoV-2 virus, the vaccine was:
  • 58% effective at preventing Covid-19 symptoms
  • 75% effective at preventing moderate or severe Covid-19
  • 100% effective against severe Covid-19 disease, including hospitalizations
New studies bring BA.2 variant into sharper focus
The new vaccine posted lower numbers against symptomatic illness than the mRNA vaccines made by Pfizer and Moderna, but it was also tested under different conditions, when the new variants were circulating.
"We're very pleased with these data," said Thomas Triomphe, an executive vice president at Sanofi. "No other global Phase 3 efficacy study has been undertaken during this period with so many variants of concern, including Omicron, and these efficacy data are similar to recent clinical data from authorized vaccines."
The companies said the vaccine performed well on its own and as a mix-and-match booster, bumping neutralizing antibodies by 18- to 30-fold when given to people who'd gotten Pfizer, Moderna or adenovirus-vector vaccines like the Johnson & Johnson and AstraZeneca shots. The manufacturers say there were no safety issues identified in the trials.
A company spokesperson says that the most likely role for the vaccine in the US and European markets — where so many people have completed their initial vaccine series — will be as a booster.

The top-line study results were posted in company news releases. The manufacturers say full results from the trials will be published this year.
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The vaccine was developed using $2.1 billion in funding from Operation Warp Speed, the landmark effort to speed effective vaccines against Covid-19 to the US and the rest of the world. The company says it has produced and released 100 million doses and plans to supply up to 400 million more doses.

Vidprevtyn development was delayed after results from an initial formulation showed that it didn't generate a robust immune response in older adults. The companies reformulated and began testing again. The latest results come from a phase 3 trial started in May 2021 and reflect real-world tests of the shots against several variants, including Delta and Omicron, according to a Sanofi spokesperson.
 
In other words...it probably is the Wu-flu China virus after all. Thanks for confirming the obvious.

"In an interview with FOX News, Moderna CEO Stephane Bancel was asked about a study published by the Frontiers in Virology, which determined that COVID-19 matches a genetic sequence of DNA patented by Moderna.
He said: "My scientists are looking into those data to see how accurate they are or not. As I've said before, the hypothesis of an escape from a lab by an accident is possible. Humans make mistakes."
"So it is possible that the Wuhan lab in China was working on virus enhancement or gene modification, and then there's an accident where somebody was infected in a lab and then infected family and friends."


It was an accident, people. Accident! Just in time too.
 
"In an interview with FOX News, Moderna CEO Stephane Bancel was asked about a study published by the Frontiers in Virology, which determined that COVID-19 matches a genetic sequence of DNA patented by Moderna.
He said: "My scientists are looking into those data to see how accurate they are or not. As I've said before, the hypothesis of an escape from a lab by an accident is possible. Humans make mistakes."
"So it is possible that the Wuhan lab in China was working on virus enhancement or gene modification, and then there's an accident where somebody was infected in a lab and then infected family and friends."


It was an accident, people. Accident! Just in time too.
I have believed this all along.

We're still being lied to, and our own government is as bad as anyone.
 
There is something hokey about the official UK.com reports. My daughter found one several months ago that stated that anyone with the triple vax will never have natural immunity again for anything. That is just total BS, but it had an official looking UK.com url with it which I believe some anti-vaxer's have corrupted somehow to look authentic. I wouldn't much faith in UK news reports on the internet.
 
I try to stay away from reports that score high on the BS scale. All sides have lots of that on the internet.

Having said...I have seen credible evidence that the vaccinated fared considerably worse against Omicron than the unvaccinated. But it's not because they were vaccinated, it was because Omicron went back and got a lot of people who had never had COVID and didn't have natural immunity. Despite what many say, natural immunity from previous infection fared much better against Omicron than the vaccine did. The vaccine, though I think it kept a lot of people from getting the original virus and probably kept many people who got the Delta from dying; it didn't do crap against Omicron.

The vaccine did it's job for awhile, but I think it's close to worthless at this point. I've said from the start that herd immunity from previous infection will be the only way to beat this thing.
 
There is something hokey about the official UK.com reports. My daughter found one several months ago that stated that anyone with the triple vax will never have natural immunity again for anything. That is just total BS, but it had an official looking UK.com url with it which I believe some anti-vaxer's have corrupted somehow to look authentic. I wouldn't much faith in UK news reports on the internet.
I will agree with you there, just never know who or what to trust these days.
 
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Just when you thought it was safe to come out:


Right on schedule to arrive here by mid-September, just in time to send out mail-in ballots....for your safety of course.

Their Zero covid techniques for control sound good, but in reality, its' gonna get in and now they have a completely unprotected population, with few having had the virus and the vaccines not preventing the virus at all. This is going to continue to happen and each shutdown will be a hit to their economy. Omicron, with it's reduced sickness may help them if they let it spread, their pride will not let them reverse a decision.

However, as long as they do shutdowns, these closing will hurt the world as well. SInce this city is a tech hub, I can see it impacting chips and electronics even more. Guess I need to go ahead and get my TV for the Theater room, they are not going to get any cheaper.
 
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